Your genome comes first.
Everything else follows.
3.2 billion base pairs. Longevity AI–interpreted and continuously updated as science advances. The permanent foundation for a longer, healthier life.
of serious disease risk
is influenced by genetics
Most of it is invisible to standard testing.
Your genome already knows.
Risk is written in your DNA long before symptoms appear.
Most tests read fragments.
Whole genome sequencing reads everything.
Most tests sample less than 1% of your genome. We analyze all 3.2 billion base pairs.
Complete Coverage
All 3.2 billion base pairs — not pre-selected regions or a genotyping chip.
Clinical-Grade Accuracy
30× sequencing depth. Clinical-grade accuracy backed by 50,000+ genomes in HLI's database.
Actionable Insights
200+ conditions, 200+ medications, and carrier status — interpreted by Longevity AI.
Lifetime Value
Re-analyzed as science advances. New gene-disease associations applied to your genome automatically.
| Human Longevity | Targeted Panels | Consumer Tests | |
|---|---|---|---|
| Genome coverage | 100% — all 3.2B base pairs | ~0.1% | <0.02% |
| Coverage depth | 30× clinical-grade | Varies | — |
| Hereditary disease risk | 200+ conditions | Panel-specific only | Select conditions |
| Pharmacogenomics | 200+ medications | Rarely included | — |
| Carrier status | 200+ conditions | Panel-dependent | Very limited |
| AI interpretation | Longevity AI clinical review | Varies | — |
| Price | $599 — one time | $300–$5,000+ | $99–$229 |
Four areas.
One test.
From saliva to insights in three weeks
Order
2-minute checkout. Kit delivered to your door in 2–3 days. $599, no subscription required.
Collect
Simple saliva sample at home. No clinic visit, no blood draw, no referral needed.
Analyze
CLIA-certified lab sequences your genome. Longevity AI interprets billions of variants against HLI's database of 50,000+ genomes.
Access
Secure portal and app with your full results and Longevity AI insights. Your genome, sequenced once — informative for life.
What knowing your genome changes
“Pharmacogenomics showed my genes couldn't metabolize SSRIs. We switched — it worked immediately. I wish I had done this test first.”
“Genomics found my Lynch Syndrome before symptoms. I started screening early — and caught two precancerous polyps. That test gave me a 20-year head start.”
“We learned we were both CF carriers before pregnancy. It completely changed our options. We never would have known without whole genome sequencing.”
“Pharmacogenomics showed my genes couldn't metabolize SSRIs. We switched — it worked immediately. I wish I had done this test first.”
“Genomics found my Lynch Syndrome before symptoms. I started screening early — and caught two precancerous polyps. That test gave me a 20-year head start.”
“We learned we were both CF carriers before pregnancy. It completely changed our options. We never would have known without whole genome sequencing.”
Human Longevity was built on a new foundation for medicine: the genome.
Led by the scientist who sequenced the first human genome, our approach starts where traditional medicine doesn't — at the level where risk begins.
“Sequencing the human genome changed what medicine could see. Now, it's about acting on that information earlier.”
- Led the first complete human genome sequence (2000)
- Founded Celera Genomics and the J. Craig Venter Institute
- National Medal of Science · Time 100 Most Influential
- Built one of the largest genomic datasets in the world
This is where our model of medicine begins.
One price. Everything included.
No subscriptions. No add-ons. No hidden fees.
One-time. No subscription.
- ✓ 30× whole genome sequencing
- ✓ Disease risk — 200+ conditions
- ✓ Medication response — 200+ drugs
- ✓ Carrier screening — 200+ conditions
- ✓ Longevity AI interpretation in plain language
HIPAA-compliant · Data never sold
Go deeper on what your genome reveals
Why Your Medications May Not Be Working — And What Your Genes Can Tell You
30–50% of medications fail due to genetic variation. Know which drugs will work for your biology before you take them.
Read article →How Genomic Risk Scores Detect Cancer and Heart Disease Decades Before Symptoms
From BRCA1/2 to polygenic heart scores to APOE Alzheimer's risk — what hereditary analysis reveals and why it changes care.
Read article →The Genetic Information Most Couples Never Have — Until It's Too Late
Everyone carries 2–3 disease-causing variants. Most never know until they have an affected child. Here's what whole genome screening covers.
Read article →