What is White Matter Hyperintensities?
Health Nucleus clients enroll presumed to be healthy, but some are found through our integrated assessments to have asymptomatic or pre-symptomatic health concerns, which now detected, can be treated through standard medical care. White Matter Hyperintensities is one example.
White Matter Hyperintensities
Definition: Nonspecific changes to the blood vessels in the white matter tissue of the brain that cause a bright appearance on a brain Computed Tomography (CT) scan or Magnetic Resonance Imaging (MRI).
- High blood pressure (hypertension)
- High cholesterol (hypocholesteremia)
- Insulin resistance -> Diabetes, Obesity
- Coronary Artery Disease (CAD)
- Chronic Kidney Disease
- Alcohol use
- History of stroke
*Not everyone of age experience hyperintensities
Possible Disease Associations:
- Decreased physical function (i.e. walking)
Lifestyle Modifications to help prevent further progression:
- Smoking cessation
- Drinking in moderation
- Diet improvement
- Maintain a healthy weight
- Manage blood pressure
Debette, S. & Markus, H.S. (2010). The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. British Medical Journal, 341. doi: https://dx.doi.org/10.1136/bmj.c3666
Van Elderen, S.G., et al. (2010). Aortic stiffness is associated with cardiac function and cerebral small vessel disease in patients with type 1 diabetes mellitus: Assessment by magnetic resonance imaging. European Radiology, 20(5): 1132-1138. doi: https://dx.doi.org/10.1007/s00330-009-1655-4
Wardlaw, J.M., Valdes Hernandez, M. C., & Munoz-Maniega, S. (2015). What are white matter hyperintensities made of? Journal of the American Heart Association, 4(6). doi: https://dx.doi.org/10.1161/JAHA.114.001140